Holzapfel is a surname. Notable people with the surname include:
Beate Holzapfel (born 1966), retired West German high jumper Brigitte Holzapfel (born 1958), retired West German high jumper Friedrich Holzapfel (1900–1969), German politician Hartmut Holzapfel (1944–2022), former Hessian Minister of Culture, Chairman of the Hessian Council on Literature
James W. Holzapfel (born 1944), American Republican Party politician, served in the New Jersey General Assembly Klaus-Jürgen Holzapfel (1930–2025), German publisher Riley Holzapfel (born 1988), Canadian professional ice hockey player Rudi Holzapfel (1938–2005), Irish poet and teacher Rudolf Maria Holzapfel (1874–1930), Poland-born Austrian psychologist, philosopher
See also Holzappel