Francisco Álvarez may refer to:
Arts and Entertainment Francisco Álvarez (actor) (1892–1960), Argentine actor Francisco C. Álvarez (1903–1963), Filipino actor and playwright
Politics Francisco Álvares (c. 1465–1536/41), Portuguese missionary and explorer Francisco Álvarez-Cascos (born 1947), Spanish civil engineer and politician
Sportspeople Francisco Álvarez (beach volleyball) (born 1969), Cuban beach volleyball player Francisco Álvarez (footballer, born 1982), Salvadoran footballer Francisco Álvarez (footballer, born 2000), Argentine defender for San Martín de San Juan Francisco Álvarez (baseball) (born 2001), Venezuelan baseball player
Other uses Francisco Álvarez Martínez (1925–2022), cardinal in the Roman Catholic Church General Francisco Álvarez, a town in the Canendiyú department of Paraguay