The Mistress may refer to:

Film and television The Mistress (1927 film), a German silent film The Mistress (1953 film), or Vassa Zheleznova, a Soviet film The Mistress (1962 film), a Swedish film The Mistress (2012 film), a Filipino film The Mistress (TV series), a 1985–1987 British sitcom

Doctor Who characters Missy (Doctor Who), a female incarnation of the Master character in Doctor Who The Mistress, a depiction of Romana II in a series of Doctor Who audioplays

Music The Mistress, a mixtape by Jay Sean, 2011 "The Mistress", a song by Charlotte Church from Two, 2013 "The Mistress", a track by Jesper Kyd from the film Tumbbad, 2018

See also Mistress (disambiguation)