Holyoke is a city in Hampden County, Massachusetts, United States.
Holyoke may also refer to: Holyoke, Colorado, a home rule municipality in Phillips County, Colorado Holyoke Publishing, an American comic book publisher Holyoke Range, a traprock mountain range in Massachusetts Mount Holyoke, a mountain in the Holyoke Range Elizur Holyoke, namesake of Holyoke, Massachusetts Keith Holyoake, a former Prime Minister of New Zealand Holyoke, Iowa, fictional setting of the 1999 film Whiteboyz Holyoke station, an Amtrak station Holyoke Heritage State Park Holyoke Automobile Company
See also Holyoake, a surname Holyoak, a surname Holyoke Blue Sox, a baseball team in Holyoke, Massachusetts Holyoke Millers, a baseball team in Holyoke, Massachusetts Holyoke Community College, a college in Holyoke, Massachusetts Holyoke Mall at Ingleside, a mall in Holyoke, Massachusetts Mount Holyoke College, a liberal arts college in South Hadley, Massachusetts