Real Chemistry, formerly known as W2O Group, is a global provider of marketing and analytics services, including public relations, to the healthcare and technology industries. Founded by Jim Weiss in 2001, Real Chemistry is an American company with global offices in Europe and Canada.

Corporate history Real Chemistry was founded as WeissComm Partners in 2001 by Jim Weiss as a one-person marketing consulting firm, with clients primarily in the healthcare industry. His firm grew quickly until 2008. According to Weiss, less favorable conditions in the healthcare industry led to a series of layoffs.

In response, the following year Weiss acquired creative services firm ODA and social media marketing firm, Common Sense Media Group, in order to diversify his interests and reduce reliance on the healthcare industry. That same year, Weiss re-formed the company under the acronym WCG, consolidating the two acquisitions under a new corporate umbrella. The acquired companies and the firm's revenues continued growing. By 2011 it had annual revenues of $48 million.

In 2012, WCG was re-structured again under a new holding company called W2O Group, which was made up of three companies: WCG, W2O Ventures, and Twist Mktg. The fourth company in the holding group, Brewlife, was formed the following year to focus on startup companies. The holding group had $75 million in annual revenues by 2013 and $82.6 million in 2014. In 2014 and 2015, W2O opened new offices in major U.S. and European cities.

In May 2016, a private-equity firm called Mountaingate Capital made an investment in W2O Group, which funded a series of acquisitions. Seven months after acquiring Fox Communications, W2O Group laid off founder Lynn Fox, who sued alleging gender discrimination.The lawsuit was dismissed with prejudice in May 2017: Case Info & Dismissal

In 2012, The Weiss Center was established at the S.I. Newhouse School of Public Communications at Syracuse University as a partnership between the university and Real Chemistry. The center aims to immerse students digital media education by developing programming in healthcare communications, influencer marketing, artificial intelligence, and analytics, focusing on their influence on society and business.https://newhouse.syracuse.edu/centers/weiss-center/about/

In June 2019, New Mountain Capital acquired an interest in W2O Group for an undisclosed amount. Following the acquisition, the company acquired Elysia Group, Discern Health and 21GRAMS.

The company acquired starpower LLC, an entertainment marketing agency, in 2020. In January 2021, Swoop, Inc., which specializes in pharmaceutical IT, and IPM.ai, a data and analytics company, were both acquired.

In March 2021, W2O Group was rebranded as Real Chemistry, and all subsidiaries were consolidated into the newly unified company. As a result of rapid acquisition activity in 2019, Real Chemistry has grown to employ over 2,000 people in 10 locations worldwide.

In January 2022, Shankar Narayanan took over as CEO, and founder Jim Weiss became chairman.

In April 2022, Real Chemistry acquired the conversational AI company conversationHEALTH.

In March 2023, Real Chemistry acquired TI Health, a data-driven marketing and predictive analytics company.

Acquisitions DateCompanyDescriptionReferences2009ODACreative services2009Common Sense Media GroupSocial media marketing firm2012RavelData analytics; based in Austin2012VM FoundryWeb and mobile development; based in Austin2013Partners for Medical EducationMedical consultation2015ARC2 Communications & MediaBoutique public relations firm; based in Los Angeles2015VintankSocial media and CRM software company2016Pure CommunicationsMarketing consultancy2016Marketeching SolutionsSocial listening2017Sentient InteractiveDigital media and analytics 2019Arcus MediaMedical analytics2019ISO HealthMedical communications company2019Radius Digital ScienceScientific digital creative agency2020Symplur LLCSocial media analytics2020Discern HealthHealth Economics and Outcomes Research (HEOR) consulting firm2020Elysia Group LLCHealth Economics and Outcomes Research (HEOR) consulting firm202021GRAMSPharmaceutical marketing agency2020starpower LLCEntertainment marketing agency 2021Swoop, Inc.Pharmaceutical IT company2021IPM.aiData and analytics company2022conversationHEALTHPharmaceutical AI company2023TI HealthPredictive analytics company

Operations and services Real Chemistry provides marketing and tech-enabled global health services to healthcare and technology companies. The company operated through five subsidiaries: WCG, Twist, Pure, Sentient and Marketeching, but has since unified into Real Chemistry. WCG was the public relations arm. As of 2012, it was responsible for about 80 percent of the company's revenue. Twist is a 50-person division that initially served largely as a conflict and analytics division. The Brewlife division serves the company's startup and emerging technology clientele.

Real Chemistry is the second largest PR firm by revenue in O'Dwyer's annual rankings of U.S. agencies and is the largest in the healthcare sector as of 2023. More than 90 percent of its revenues are from U.S.-based clients. Healthcare tends to be its fastest growing practice area and was the firm's focus early on, though more recently the analytics practice has taken a larger role.

According to PR Week, the company's most-used services include "PR, analytics, and its CCX creative unit." It also started a multicultural practice in early 2015. One of Real Chemistry's software services is MDigitalLife, which stores data on the online activity of doctors and patients. It is used by pharmaceutical companies to understand sentiment in the healthcare field.

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