Antinori is an Italian surname. Notable people with the surname include:
Edgardo Antinori (born 1969), Argentine judoka Ignacio Antinori (1885–1940), Italian-born American mobster Luigi Antinori, 18th century singer Orazio Antinori (1811–1882), Italian explorer and zoologist Severino Antinori (born 1945), Italian gynecologist and embryologist Vincenzo Antinori (1792–1865), Italian science administrator