Edward Radclyffe may refer to:
Edward Radclyffe, 6th Earl of Sussex (c. 1559–1643), MP for Petersfield, Bedfordshire and Portsmouth Edward Radclyffe, 2nd Earl of Derwentwater (1655–1705), also MP for Petersfield, Bedfordshire and Portsmouth Edward Radclyffe (1809–1863), British engraver
See also Edward Radcliffe-Nash, British horse rider