C. africana may refer to:

Chlamydoselachus africana, the southern African frilled shark, a shark species Clathrina africana, a sponge species Claviceps africana, a fungus sorghum pathogen species Cleopatra africana, a freshwater snail species Cnemaspis africana, a gecko species found in Central Africa Chrysomyza africana, a picture-winged fly species Constricta africana, a fungus species Coralliophila africana Cordia africana, a tree species Cunninghamella africana, a fungus species

Synonyms Carissa africana, a synonym for Carissa spinarum, the conkerberry or bush plum, a large shrub species

See also Africana (disambiguation)