Downshire may refer to the following:
Antarctica Downshire Cliffs
Northern Ireland County Down Downshire Hospital, psychiatric hospital at Downpatrick, County Down Downshire School, Carrickfergus, County Antrim Downshire railway station, Carrickfergus, County Antrim Downshire Young Men F.C., Hillsborough, County Down Downshire, electoral area of Lisburn City Council Marquess of Downshire
England Downshire Hill, street in Hampstead, London