LTSS can mean: Lutheran Theological Southern Seminary Livermore Time Sharing System Long-Term Support and Service (or Long-Term Services and Support) in medical language (also long-term care), concerning people with disabilities in data-processing language, it means extended support of software (usually enterprise software) Looney Tunes Super Stars, a series of Looney Tunes DVDs Lord Tweedsmuir Secondary School, a high school near Vancouver, British Columbia
LTSs is also sometimes used as the plural of LTS, which can mean: Large technical system Labelled transition system