This is a list of films which have placed number one at the weekend box office in the United States during 2010.

Number-one films †This implies the highest-grossing movie of the year. Weekend end date Film Gross Notes 1 Avatar † $68,490,688 Avatar broke Spider-Mans record ($45 million) for the highest third weekend gross of all time, and Cloverfields record ($40.1 million) for the highest weekend gross in January. 2 $50,306,217 Avatar broke Titanics record ($28.7 million) for the highest fourth weekend gross of all time. It also became the first film since The Dark Knight to top the box office for four consecutive weekends. It also broke Pirates of the Caribbean: Dead Man's Chests record (63 days) for the fastest film to gross $1 billion worldwide, crossing the mark in 19 days. 3 $42,785,612 Avatar broke Titanics record ($30 million) for the highest fifth weekend gross of all time, and Cloverfields record ($40.1 million) for the highest Martin Luther King Jr. Day long-weekend gross ever. It also became the first film since The Sixth Sense to top the box office for five consecutive weekends and the first film since Signs to top the box office in its fifth weekend. 4 $34,944,081 Avatar broke Titanics record ($25.5 million) for the highest sixth weekend gross of all time. It also became the first film since Titanic to top the box office for six consecutive weekends. With this intake, it became the highest-grossing film of all time. 5 $31,280,029 Avatar broke Titanics record ($25.9 million) for the highest seventh weekend gross of all time. It also became the first film since Titanic to top the box office for seven consecutive weekends and the first film since The Passion of the Christ to top the box office in its seventh weekend. 6 Dear John $30,468,614 7 Valentine's Day $56,260,707 Valentine's Day broke Ghost Riders record ($45.4 million) for the highest President's Day weekend debut. 8 Shutter Island $41,062,440 9 $22,665,205 10 Alice in Wonderland $116,101,023 Alice in Wonderland broke 300s record ($70.9 million) for the highest weekend debut in March and Fast & Furious record ($71 million) for the highest weekend debut for a spring release. It also broke Spider-Man'''s record ($114.8 million) for the highest weekend debut for a non-sequel, Harry Potter and the Goblet of Fires record ($102.7 million) for the highest weekend debut for a live-action fantasy film, and Avatars record ($77 million) for the highest weekend debut for a 3-D film. || |- | 11 || || $62,714,076 || || |- | 12 || || $34,189,969 || || |- | 13 || || How to Train Your Dragon || $43,732,319 || || |- | 14 || || rowspan="2" | Clash of the Titans || $61,235,105 || Clash of the Titans broke Scary Movie 4's record ($40.2 million) for the highest Easter weekend debut. || |- | 15 || || $26,633,209 || Initial estimates had Date Night ahead of Clash of the Titans. || |- | 16 || || Kick-Ass || $19,828,687 || Initial estimates had How to Train Your Dragon ahead of Kick-Ass. || |- | 17 || || How to Train Your Dragon || $15,350,213 || How to Train Your Dragon reclaimed the #1 spot in its fifth weekend of release. It became the first film since Avatar to top the box office in its fifth weekend. ||

| 18 || || A Nightmare on Elm Street || $32,902,299 || || |- | 19 || || rowspan="2" | Iron Man 2 || $128,122,480 || Iron Man 2 had the highest weekend debut of 2010. || |- | 20 || || $52,041,005 || || |- | 21 || || rowspan="3" | Shrek Forever After || $70,838,207 || || |- | 22 || || $43,311,063 || || |- | 23 || || $25,486,465 || || |- | 24 || || The Karate Kid || $55,665,805 || || |- | 25 || || rowspan="2" | Toy Story 3 || $110,307,189 || Toy Story 3 broke Transformers: Revenge of the Fallens record ($109 million) for the highest weekend debut in June and Finding Nemos record ($70.3 million) for the highest opening weekend for a G-rated film. Its $41.1 million opening day gross broke Shrek the Thirds record ($38 million) for the biggest single day gross for an animated film. || |- | 26 || || $59,337,669 || || |- | 27 || || The Twilight Saga: Eclipse || $64,832,191 || The Twilight Saga: Eclipses $30.1 million gross from midnight showings broke The Twilight Saga: New Moons record ($26.3 million) for the highest midnight opening ever. It also broke Transformers: Revenge of the Fallens records for the highest midnight gross in IMAX ($959,000) with $1 million and the highest Wednesday gross of all-time with $68.5 million. || |- | 28 || || Despicable Me || $56,397,125 || ||

| 29 || || rowspan="3" | Inception || $62,785,337 || || |- | 30 || || $42,725,012 || || |- | 31 || || $27,485,245 || || |- | 32 || || The Other Guys || $35,543,162 || || |- | 33 || || rowspan="2" | The Expendables || $34,825,135 || ||

| 34 || || $16,968,032 || ||

| 35 || || Takers || $20,512,304 || Initial estimates had The Last Exorcism ahead of Takers. || |- | 36 || || The American || $13,177,790 || ||

| 37 || || Resident Evil: Afterlife || $26,650,264 || || |- | 38 || || The Town || $23,808,032 || ||

| 39 || || Wall Street: Money Never Sleeps || $19,011,188 || || |- | 40 || || rowspan="2" | The Social Network || $22,445,653 || || |- | 41 || || $15,451,991 || || |- | 42 || || Jackass 3D || $50,353,641 || Jackass 3D broke Scary Movie 3s records ($48.1 million) for the highest weekend debut in October and for any fall release. Jackass 3D also broke Brünos record ($30.4 million) for the biggest weekend debut for a docu-comedy. || |- | 43 || || Paranormal Activity 2 || $40,678,424 || Paranormal Activity 2 broke Friday the 13ths record ($40.5 million) for the highest weekend debut for a horror film. || |- | 44 || || Saw 3D || $22,530,123 || || |- | 45 || || rowspan="2" | Megamind || $46,016,833 || || |- | 46 || || $29,120,461 || || |- | 47 || || rowspan="2" | Harry Potter and the Deathly Hallows – Part 1 || $125,017,372 || Harry Potter and the Deathly Hallows – Part 1s $1.4 million midnight gross in IMAX broke The Twilight Saga: Eclipses record ($1 million) for the highest midnight gross in IMAX. It also broke Alice in Wonderlands record ($116.1 million) for the highest weekend debut for a live-action fantasy film. || |- | 48 || || $49,087,101 || In second place, Tangleds $48.8 million opening weekend broke The Lion Kings records ($40.9 million) for the highest weekend debuts for a Walt Disney Animation Studios film and for a musical animated film. It also broke High School Musical 3: Senior Years record ($42 million) for the highest weekend debut for a musical film. || |- | 49 || || Tangled || $21,608,891 || Tangled reached #1 in its second weekend of release. || |- | 50 || || The Chronicles of Narnia: The Voyage of the Dawn Treader || $24,005,069 || || |- | 51 || || Tron: Legacy || $44,026,211 || || |- | 52 || || rowspan="2" | Little Fockers'' $30,833,665 53 $25,766,485

Highest-grossing films

Calendar Gross Highest-grossing films of 2010 by Calendar Gross Rank Title Studio(s) Actor(s) Director(s) Gross 1. Avatar 20th Century Fox Sam Worthington, Zoe Saldaña, Stephen Lang, Michelle Rodriguez and Sigourney Weaver James Cameron $466,141,929 2. Toy Story 3Walt Disney Studios voices of Tom Hanks, Tim Allen, Joan Cusack, Don Rickles, Wallace Shawn, John Ratzenberger, Estelle Harris, Blake Clark, Jeff Pidgeon, Ned Beatty, Michael Keaton, Jodi Benson and John Morris Lee Unkrich $410,171,027 3. Alice in Wonderland Johnny Depp, Anne Hathaway, Helena Bonham Carter, Crispin Glover, Matt Lucas, Mia Wasikowska, Alan Rickman, Stephen Fry, Michael Sheen and Timothy Spall Tim Burton $332,430,200 4. Iron Man 2 Paramount Pictures Robert Downey Jr., Gwyneth Paltrow, Don Cheadle, Scarlett Johansson, Sam Rockwell, Mickey Rourke and Samuel L. Jackson Jon Favreau $312,433,331 5. The Twilight Saga: Eclipse Summit Entertainment Kristen Stewart, Robert Pattinson, Taylor Lautner, Bryce Dallas Howard, Billy Burke and Dakota Fanning David Slade $300,531,751 6. InceptionWarner Bros. Pictures Leonardo DiCaprio, Ken Watanabe, Joseph Gordon-Levitt, Marion Cotillard, Elliot Page, Tom Hardy, Cillian Murphy, Tom Berenger and Michael Caine Christopher Nolan $292,558,188 7. Harry Potter and the Deathly Hallows – Part 1 Daniel Radcliffe, Rupert Grint, Emma Watson, Helena Bonham Carter, Robbie Coltrane, Warwick Davis, Ralph Fiennes, Michael Gambon, Brendan Gleeson, Richard Griffiths, John Hurt, Rhys Ifans, Jason Isaacs, Alan Rickman, Fiona Shaw, Timothy Spall, Imelda Staunton and David Thewlis David Yates $280,230,127 8. Despicable Me Universal Pictures voices of Steve Carell, Jason Segel, Russell Brand, Kristen Wiig, Miranda Cosgrove, Will Arnett and Julie Andrews Pierre Coffin and Chris Renaud $251,083,040 9. Shrek Forever AfterParamount Pictures voices of Mike Myers, Eddie Murphy, Cameron Diaz, Antonio Banderas, Julie Andrews, John Cleese, Walt Dohrn, Jane Lynch, Jon Hamm, Craig Robinson, Lake Bell, Mary Kay Place, Kathy Griffin and Kristen Schaal Mike Mitchell $238,736,787 10. How to Train Your Dragon voices of Jay Baruchel, Gerard Butler, Craig Ferguson, America Ferrera, Jonah Hill, Christopher Mintz-Plasse, T. J. Miller, Kristen Wiig and David Tennant Chris Sanders and Dean DeBlois $217,581,231

In-Year Release + Highest-grossing films of 2010 by In-year release Rank Title Distributor Domestic gross 1. Toy Story 3 Disney $415,004,880 2. Alice in Wonderland $334,191,110 3. Iron Man 2 Paramount $312,433,331 4. The Twilight Saga: Eclipse Summit $300,531,751 5. Harry Potter and the Deathly Hallows – Part 1 Warner Bros. $295,983,305 6. Inception $292,576,195 7. Despicable Me Universal $251,513,985 8. Shrek Forever After Paramount $238,736,787 9. How to Train Your Dragon $217,581,231 10. Tangled Disney $200,821,936

+ Highest-grossing films by MPAA rating of 2010 G Toy Story 3 PG Alice in Wonderland PG-13 Iron Man 2 R The King's Speech

See also List of American films — American films by year Lists of box office number-one films

References

Chronology