Lesch is a surname. Notable people with the surname include:
Carl Lesch, American Roman Catholic educator Gabriela Lesch, German runner George Henry Lesch, American businessman Harald Lesch, German physicist John Lesch, American politician Karin Lesch, Swiss-German actress Klaus-Peter Lesch, German psychiatrist Michael Lesch, Jewish American physician and medical educator Willi Lesch, German alpine skier
See also Lesh, a surname and given name