D’Antonio or d'Antonio is a surname of Italian origin. It derived from the Antonius root name. Notable people with the surname include:
Biagio d'Antonio (1446–1516), Italian Renaissance painter Gino D'Antonio (1927–2006), Italian comic writer and artist Michael D'Antonio (born 1955), American author and journalist Mike D'Antonio (contemporary), American metalcore musician Nunziata d'Antonio (1468–1525), Florentine artist Trent D'Antonio (born 1985), Australian professional baseball player Antonio di Nunziato d'Antonio, birthname of Anthony Toto, (1498–1554), Italian painter and architect
See also D'Antoni, Italian surname Dantonio, Italian surname di Antonio, Italian surname Emile de Antonio
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