Arsames (Old Persian Aršāma, ) was an Achaemenid Persian satrap of Cilicia in 334/3 BC. He succeeded Mazaeus in this position. He took part in the Battle of Granicus where he fought with his cavalry on the left wing, along with Arsites and Memnon of Rhodes.Diodorus 17.19.4 He was able to survive that battle and flee to the capital of Cilicia Tarsus. There he was planning a scorched-earth policy according to that of Memnon which caused the native Cilician soldiers to abandon their posts.Curtius Rufus 3.4.3-15 He also decided to burn Tarsus to the ground so as not to fall in the hands of Alexander but was prevented from doing so by the speedy arrival of Parmenion with the light armored units who took the city.Arrian 2.4.5-6Curtius Rufus 3.4.14 After that, Arsames fled to Darius who was at this time in Syria.Arrian 2.4.6 He was slain at the battle of Issus (modern-day Turkey) in 333 BC.Arrian 2.11.8Alexander of Macedon, 356-323 B.C.: a historical biography By Peter Green

He was succeeded by Balacrus, a bodyguard of Alexander the Great, who became the Hellenistic satrap of Cilica.

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