Cyril II may refer to:
Pope Cyril II of Alexandria (ruled 1078–1092) Patriarch Cyril II of Alexandria, Greek Patriarch of Alexandria in the 12th century Cyril II of Kyiv, the metropolitan of Kyiv from 1242 until his death Cyril II of Constantinople, Ecumenical Patriarch of Constantinople in 1633, 1635–1636 and 1638–1639 Patriarch Cyril II of Jerusalem (ruled (1846–1872)