4Hydroxybenzaldehyde (parahydroxybenzaldehyde) is an organic compound with the formula .Merck Index, 11th Edition, 8295 Along with 2-hydroxybenzaldehyde and 3-hydroxybenzaldehyde, it is one of the three isomers of hydroxybenzaldehyde.
Synthesis, reactions, uses 4-Hydroxybenzaldehyde is prepared by reaction of phenol with chloroform, which gives isomeric hydroxybenzal chlorides. Hydrolysis of the C-Cl bonds gives the aldehyde.
4-Hydroxybenzaldehyde is a precursor to 4-hydroxyphenylglycine, which is itself a precursor to penicillins. In the Dakin oxidation, 4-hydroxybenzaldehyde reacts with hydrogen peroxide in base to form hydroquinone.
Metabolism and occurrence p-Hydroxybenzaldehyde dehydrogenase is an enzyme found in carrots (Daucus carota).
4-Hydroxybenzaldehyde is found in the orchids Gastrodia elata, Galeola faberi, and the Vanilla orchids.
See also Salicylaldehyde (2-hydroxybenzaldehyde)
References
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