Charnley is a surname. Notable people with the surname include:

Bill Charnley, English footballer Bryan Charnley (1949–1991), English artist Chic Charnley (born 1963), Scottish association football (soccer) player Dave Charnley (1935–2012), English lightweight boxer Donn Charnley (born 1928), American politician Irene Charnley (born 1960), South African businesswoman John Charnley (1911–1982), English orthopaedic surgeon Josh Charnley (born 1991), English rugby league footballer Ray Charnley (1935–2009), English association football (soccer) player Sam Charnley (1902–1977), Scottish association football (soccer) player

See also Hip prosthesis zones, including the DeLee and Charnley system