The 1941–42 season was the 20th edition of the amateur league called Liga Mayor.
Standings
The playoff match to define the title was held at Parque Asturias on May 10, 1942. Playoff match: RC España 5-4 Atlante FC
Top goalscorers PlayerClubGoals Rafael MezaMoctezuma de Orizaba20
References Mexico - List of final tables (RSSSF)