Seppelt is a German surname. Notable people with the surname include:
Benno Seppelt (1846–1931), South Australian winemaker, son of Joseph Hajo Seppelt (born 1963), German journalist Joseph Ernst Seppelt (1813–1868), founder of Seppeltsfield and the Seppelt winery in South Australia Konrad Seppelt, (born 1944) German chemist, Vice President of the Free University of Berlin
See also Seppeltsfield (disambiguation)