Wampler is a surname. Notable people with the surname include:
Fred Wampler (Congressman) (1909–1999), U.S. Representative from Indiana Fred Wampler (golfer) (1923–1985), American professional golfer who played on the PGA Tour and the Senior PGA Tour William C. Wampler (1926–2012), United States Representative from Virginia William C. Wampler, Jr. (born 1959), American politician, elected to the Senate of Virginia in 1988 William C. "Will" Wampler III (born 1991), member of the Virginia House of Delegates Wampler Pedals, manufacturer of guitar effects pedals