Van Cleave is a surname. Notable people with the surname include:
A. R. VanCleave (1889–1987), American football coach Aaron Van Cleave (born 1987), U.S./Canadian pair skater Ira Van Cleave, American football coach Nathan Van Cleave (1910–1970), American composer and orchestrator known as Van Cleave Ryan G. Van Cleave (born 1972), American author and teacher William Van Cleave (1935–2013), American political scientist, advisor to President Ronald Reagan
See also Vancleave, Mississippi, United States, a census-designated place Van Cleave, Kentucky, an unincorporated community Van Cleve Cleve (surname), includes Van Cleve Van Cleef, a surname