Naloxonazine is a potent, irreversible μ-opioid receptor antagonist.Naloxonazine dihydrochloride Naloxonazine forms spontaneously in acidic solutions of naloxazone, and may be responsible for much or all of the irreversible μ-opioid receptor binding displayed by the latter.
See also Oxymorphone-3-methoxynaltrexonazine, a similar opioid also having two complete and mirrored morphinan carbon skeletons
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