Clodius is an alternate form of the Roman nomen Claudius. It may also refer to:

Frederick Clod or Clodius (1625–after 1661), alchemist in London Gustav Clodius (1866–1944), German pastor and ornithologist Julie Clodius (1750–1805), German philosopher Karl Clodius, German World War II diplomat known for negotiating the 1941 Clodius Agreement with Turkey Robert Clodius (1921–2014), American educator and university administrator Clodius, a character in the 1834 novel The Last Days of Pompeii by Edward Bulwer-Lytton

See also Parnassius clodius, a butterfly Clodia (wife of Metellus), sister of Clodius Pulcher Leges Clodiae, legislation sponsored by Clodius Pulcher as tribune in the 1st century BC