Campano is a surname. Notable people with the surname include:
Alejandro Campano (born 1978), Spanish footballer Carlos Campano (born 1985), Spanish motorcycle racer Giovanni Campano (c. 1220–1296), one of the referents used for Campanus of Novara, Italian mathematician and astrologer Giovanni Antonio Campano (1429–1477), Italian humanist bishop Miguel Ángel Campano (1948–2018), Spanish painter