The Arizona Diamondbacks' 2010 season, the franchise's 13th season in Major League Baseball, included the team's attempt to make the playoffs for the first time since 2007. On July 1, 2010, the Arizona Diamondbacks fired Manager A. J. Hinch following a 31–48 start to the 2010 season and promoted Kirk Gibson who had served as the bench coach of the team since the 2007 season. Along with the dismissal of Hinch came the firing of General Manager Josh Byrnes.
Edwin Jackson no-hitter On June 25, 2010, in a game against the Tampa Bay Rays at Tropicana Field in St. Petersburg, Florida, Diamondbacks right-hander Edwin Jackson threw the second no-hitter in franchise history in a 1–0 victory in front of a crowd of 18,918. Jackson walked eight Rays batters and struck out six in a 149 pitch outing to complete the game, the only offense he received by his teammates came in the form of a solo home run by first baseman Adam LaRoche in the second inning.
Regular season Season standings National League West
National League Wild Card
Record vs. opponents
Game log Legend Diamondbacks Win Diamondbacks Loss Game postponed
|- bgcolor="ffbbbb" |- align="center" bgcolor="bbffbb" | 1 || April 5 || San Diego || 6–3 || Haren (1–0) || Garland (0–1) || None|| 49,192 || 1–0 |- align="center" bgcolor="ffbbbb" | 2 || April 6 || San Diego || 3–6 || Young (1–0) || Jackson (0–1) || Bell (1) || 19,177 || 1–1 |- align="center" bgcolor="bbffbb" | 3 || April 7 || San Diego || 5–3 || Boyer (1–0) || Correia (0–1) || Qualls (1) || 17,673 || 2–1 |- align="center" bgcolor="bbffbb" | 4 || April 9 || Pittsburgh || 9–1 || López (1–0) || Morton (0–1) || None|| 21,316 || 3–1 |- align="center" bgcolor="ffbbbb" | 5 || April 10 || Pittsburgh || 3–6 || Duke (2–0) || Haren (1–1) || Dotel (1) || 22,400 || 3–2 |- align="center" bgcolor="bbffbb" | 6 || April 11 || Pittsburgh || 15–6 || Jackson (1–1) || McCutchen (0–1) || None || 21,093 || 4–2 |- align="center" bgcolor="ffbbbb" | 7 || April 13 || @ Los Angeles || 9–5 || Kershaw (1–0) || Kennedy (0–1) || None || 56,000 || 4–3 |- align="center" bgcolor="bbffbb" | 8 || April 14 || @ Los Angeles || 7–9 || Rosales (1–0) || Ortiz (0–1) || None || 44,621 || 5–3 |- align="center" bgcolor="ffbbbb" | 9 || April 15 || @ Los Angeles || 6–5 || Broxton (1–0) || Boyer (1–1) || None || 39,697 || 5–4 |- align="center" bgcolor="ffbbbb" | 10 || April 16 || @ San Diego || 6–3 || Bell (1–0) || Gutiérrez (0–1) || None || 26,632 || 5–5 |- align="center" bgcolor="ffbbbb" | 11 || April 17 || @ San Diego || 5–0 || Correia (2–1) || Benson (0–1) || None || 31,324 || 5–6 |- align="center" bgcolor="ffbbbb" | 12 || April 18 || @ San Diego || 5–3 || Mujica (1–0) || Heilman (0–1) || Bell (3) || 20,634 || 5–7 |- align="center" bgcolor="ffbbbb" | 13 || April 19 || St. Louis || 2–4 || Penny (2–0) || Boyer (1–2) || Franklin (5) || 24,167 || 5–8 |- align="center" bgcolor="bbffbb" | 14 || April 20 || St. Louis || 9–7 || Haren (2–1) || Boggs (0–1) || Qualls (2) || 19,855 || 6–8 |- align="center" bgcolor="ffbbbb" | 15 || April 21 || St. Louis || 4–9 || Motte (1–1) || Qualls (0–1) || None || 19,165 || 6–9 |- align="center" bgcolor="bbffbb" | 16 || April 23 || Philadelphia || 7–4 || Benson (1–1) || Hamels (2–2) || Qualls (3) || 25,980 || 7–9 |- align="center" bgcolor="ffbbbb" | 17 || April 24 || Philadelphia || 2–3 || Contreras (1–1) || Gutiérrez (0–2) || Madson (4) || 33,323 || 7–10 |- align="center" bgcolor="bbffbb" | 18 || April 25 || Philadelphia || 8–6 || Rosales (2–0) || Herndon (0–1) || Qualls (4) || 29,296 || 8–10 |- align="center" bgcolor="bbffbb" | 19 || April 26 || @ Colorado || 3–5 || Haren (3–1) || Hammel (0–2) || Qualls (5) || 20,308 || 9–10 |- align="center" bgcolor="ffbbbb" | 20 || April 27 || @ Colorado || 12–1 || Jiménez (5–0) || Jackson (1–2) || None || 24,112 || 9–11 |- align="center" bgcolor="bbffbb" | 21 || April 28 || @ Colorado || 11–12 || Howry (1–0) || Morales (0–2) || Gutiérrez (1) || 23,773 || 10–11 |- align="center" bgcolor="bbffbb" | 22 || April 29 || @ Chicago || 5–13 || Kennedy (1–1) || Lilly (1–1) || None || 36,850 || 11–11 |- align="center" bgcolor="ffbbbb" | 23 || April 30 || @ Chicago || 11–5 || Wells (3–0) || López (1–1) || None || 37,800 || 11–12
|- bgcolor="ffbbbb" |- align="center" bgcolor="ffbbbb" | 24 || May 1 || @ Chicago || 7–5 || Marshall (1–1) || Gutiérrez (0–3) || Mármol (4) || 40,368 || 11–13 |- align="center" bgcolor="ffbbbb" | 25 || May 2 || @ Chicago || 10–5 || Gorzelanny (1–3) || Jackson (1–3) || None || 38,144 || 11–14 |- align="center" bgcolor="bbffbb" | 26 || May 3 || @ Houston || 1–9 || Valdez (1–0) || Paulino (0–4) || None || 20,370 || 12–14 |- align="center" bgcolor="bbffbb" | 27 || May 4 || @ Houston || 0–1 || Kennedy (2–1) || Oswalt (2–4) || Qualls (5) || 22,661 || 13–14 |- align="center" bgcolor="ffbbbb" | 28 || May 5 || @ Houston || 4–2 || Lindstrom (1–0) || Gutiérrez (0–4) || None || 21,030 || 13–15 |- align="center" bgcolor="bbffbb" | 29 || May 6 || @ Houston || 3–6 || Haren (4–1) || Rodríguez (1–4) || None || 21,019 || 14–15 |- align="center" bgcolor="ffbbbb" | 30 || May 7 || Milwaukee || 2–3 || Gallardo (4–2) || Jackson (1–4) || Hoffman (5) || 27,067 || 14–16 |- align="center" bgcolor="ffbbbb" | 31 || May 8 || Milwaukee || 3–17 || Wolf (3–2) || Valdez (1–1) || None || 26,877 || 14–17 |- align="center" bgcolor="ffbbbb" | 32 || May 9 || Milwaukee || 1–6 || Narveson (3–0) || Kennedy (2–2) || None || 25,358 || 14–18 |- align="center" bgcolor="ffbbbb" | 33 || May 10 || Los Angeles || 3–7 || Billingsley (3–2) || López (1–2) || None || 19,863 || 14–19 |- align="center" bgcolor="ffbbbb" | 34 || May 11 || Los Angeles || 3–13 || Ely (1–1) || Haren (4–2) || None || 21,030 || 14–20 |- align="center" bgcolor="ffbbbb" | 35 || May 12 || Los Angeles || 3–6 || Kuroda (4–1) || Jackson (1–5) || Broxton (4) || 22,714 || 14–21 |- align="center" bgcolor="ffbbbb" | 36 || May 14 || @ Atlanta || 6–5 || Wagner (2–0) || Qualls (0–2) || None || 30,657 || 14–22 |- align="center" bgcolor="bbffbb" | 37 || May 15 || @ Atlanta || 1–11 || López (2–2) || Hanson (3–3) || None || 32,718 || 15–22 |- align="center" bgcolor="ffbbbb" | 38 || May 16 || @ Atlanta || 13–1 || Hudson (4–1) || Haren (4–3) || None || 31,758 || 15–23 |- align="center" bgcolor="bbffbb" | 39 || May 17 || @ Florida || 1–5 || Jackson (2–5) || Volstad (3–4) || None || 10,870 || 16–23 |- align="center" bgcolor="ffbbbb" | 40 || May 18 || @ Florida || 8–0 || Johnson (4–1) || Buckner (0–1) || None || 13,289 || 16–24 |- align="center" bgcolor="bbffbb" | 41 || May 19 || San Francisco || 13–1 || Kennedy (3–2) || Wellemeyer (3–3) || None || 17,073 || 17–24 |- align="center" bgcolor="bbffbb" | 42 || May 20 || San Francisco || 8–7 || Heilman (1–1) || Affeldt (2–3) || Qualls (7) || 18,607 || 18–24 |- align="center" bgcolor="bbffbb" | 43 || May 21 || Toronto || 8–6 || Haren (5–3) || Morrow (3–4) || Qualls (8) || 19,531 || 19–24 |- align="center" bgcolor="bbffbb" | 44 || May 22 || Toronto || 8–5 || Jackson (3–5) || Eveland (3–4) || Qualls (9) || 32,746 || 20–24 |- align="center" bgcolor="ffbbbb" | 45 || May 23 || Toronto || 4–12 || Marcum (4–1) || Buckner (0–2) || None || 23,148 || 20–25 |- align="center" bgcolor="ffbbbb" | 46 || May 25 || @ Colorado || 3–2 || Chacín (3–2) || Kennedy (3–3) || Corpas (4) || 28,370 || 20–26 |- align="center" bgcolor="ffbbbb" | 47 || May 26 || @ Colorado || 7–3 || Jiménez (9–1) || López (2–3) || None || 26,320 || 20–27 |- align="center" bgcolor="ffbbbb" | 48 || May 27 || @ Colorado || 8–2 || Hammel (2–3) || Haren (5–4) || None || 28,353 || 20–28 |- align="center" bgcolor="ffbbbb" | 49 || May 28 || @ San Francisco || 5–0 || Cain (3–4) || Jackson (3–6) || None || 31,495 || 20–29 |- align="center" bgcolor="ffbbbb" | 50 || May 29 || @ San Francisco || 12–1 || Sánchez (3–4) || Buckner (0–3) || None || 37,400 || 20–30 |- align="center" bgcolor="ffbbbb" | 51 || May 30 || @ San Francisco || 6–5 || Wilson (1–0) || Rosa (0–1) || None || 41,394 || 20–31 |- align="center" bgcolor="ffbbbb" | 52 || May 31 || @ Los Angeles || 5–4 || Broxton (3–0) || Vásquez (0–1) || None || 45,325 || 20–32
|- bgcolor="ffbbbb" |- align="center" bgcolor="ffbbbb" | 53 || June 1 || @ Los Angeles || 1–0 || Weaver (3–1) || Gutiérrez (0–5) || None || 36,533 || 20–33 |- align="center" bgcolor="ffbbbb" | 54 || June 2 || @ Los Angeles || 1–0 || Schlichting (1–0) || Valdez (1–2) || None || 35,355 || 20–34 |- align="center" bgcolor="bbffbb" | 55 || June 4 || Colorado || 7–6 || Qualls (1–2) || Corpas (1–3) || None || 25,290 || 21–34 |- align="center" bgcolor="bbffbb" | 56 || June 5 || Colorado || 4–3 || Willis (2–2) || Chacín (3–4) || Qualls (10) || 28,138 || 22–34 |- align="center" bgcolor="ffbbbb" | 57 || June 6 || Colorado || 3–2 || Jiménez (11–1) || López (2–4) || Corpas (6) || 20,793 || 22–35 |- align="center" bgcolor="bbffbb" | 58 || June 7 || Atlanta || 7–4 || Haren (6–4) || Lowe (8–5) || Qualls (11) || 17,731 || 23–35 |- align="center" bgcolor="ffbbbb" | 59 || June 8 || Atlanta || 5–7 || Venters (1–0) || Vásquez (0–2) || Wagner (10) || 17,052 || 23–36 |- align="center" bgcolor="bbffbb" | 60 || June 9 || Atlanta || 2–1 || Heilman (2–1) || Moylan (2–1) || Qualls (12) || 19,138 || 24–36 |- align="center" bgcolor="ffbbbb" | 61 || June 10 || Atlanta || 7–11 || Moylan (2–2) || Qualls (1–3) || Wagner (11) || 26,969 || 24–37 |- align="center" bgcolor="ffbbbb" | 62 || June 11 || St. Louis || 2–5 || García (6–2) || López (2–5) || Franklin (11) || 20,629 || 24–38 |- align="center" bgcolor="bbffbb" | 63 || June 12 || St. Louis || 7–2 || Haren (7–4) || Ottavino (0–2) || None || 30,017 || 25–38 |- align="center" bgcolor="bbffbb" | 64 || June 13 || St. Louis || 7–5 || Vásquez (1–2) || McClellan (0–2) || None || 23,922 || 26–38 |- align="center" bgcolor="ffbbbb" | 65 || June 15 || @ Boston || 6–3 || Buchholz (9–4) || Kennedy (3–4) || Papelbon (14) || 37,459 || 26–39 |- align="center" bgcolor="ffbbbb" | 66 || June 16 || @ Boston || 6–2 || Lester (8–2) || López (2–6) || Papelbon (15) || 37,452 || 26–40 |- align="center" bgcolor="ffbbbb" | 67 || June 17 || @ Boston || 8–5 || Lackey (8–3) || Haren (7–5) || None || 37,544 || 26–41 |- align="center" bgcolor="ffbbbb" | 68 || June 18 || @ Detroit || 7–5 || Coke (5–0) || Qualls (1–5) || Valverde (15) || 37,438 || 26–42 |- align="center" bgcolor="bbffbb" | 69 || June 19 || @ Detroit || 5–6 || Jackson (4–6) || Porcello (4–7) || Heilman (1) || 40,681 || 27–42 |- align="center" bgcolor="ffbbbb" | 70 || June 20 || @ Detroit || 3–1 || Scherzer (4–6) || Kennedy (3–5) || Valverde (16) || 41,417 || 27–43 |- align="center" bgcolor="bbffbb" | 71 || June 21 || Yankees || 10–4 || López (3–6) || Burnett (6–6) || None || 47,229 || 28–43 |- align="center" bgcolor="ffbbbb" | 72 || June 22 || Yankees || 3–9 || Pettitte (9–2) || Haren (7–6) || None || 45,776 || 28–44 |- align="center" bgcolor="ffbbbb" | 73 || June 23 || Yankees || 5–6 || Rivera (1–1) || Rosa (0–2) || None || 46,325 || 28–45 |- align="center" bgcolor="bbffbb" | 74 || June 25 || @ Tampa Bay || 0–1 || Jackson (5–6) No-Hitter || Niemann (6–2) || None || 18,918 || 29–45 |- align="center" bgcolor="ffbbbb" | 75 || June 26 || @ Tampa Bay || 5–3 || Price (11–3) || Kennedy (3–6) || Soriano (18) || 23,945 || 29–46 |- align="center" bgcolor="bbffbb" | 76 || June 27 || @ Tampa Bay || 1–2 || López (4–6) || Davis (5–9) || Heilman (2) || 25,442 || 30–46 |- align="center" bgcolor="ffbbbb" | 77 || June 28 || @ St. Louis || 6–5 || Motte (3–2) || Heilman (2–2) || None || 41,578 || 30–47 |- align="center" bgcolor="ffbbbb" | 78 || June 29 || @ St. Louis || 8–0 || Wainwright (11–5) || Willis (2–3) || None || 38,736 || 30–48 |- align="center" bgcolor="bbffbb" | 79 || June 30 || @ St. Louis || 2–4 || Enright (1–0) || Suppan (0–4) || Heilman (3) || 36,962 || 31–48
|- bgcolor="ffbbbb" |- align="center" bgcolor="bbffbb" | 80 || July 2 || Los Angeles || 12–5 || Jackson (6–6) || Kuroda (7–6) || None || 23,115 || 32–48 |- align="center" bgcolor="ffbbbb"