LCMS refers to the Lutheran Church – Missouri Synod, a conservative Lutheran body in the United States.
LCMS may also refer to:
Science and technology Liquid chromatography–mass spectrometry, a chemical analysis technique Learning content management system LittleCMS, an open-source color management system
Organizations Lindero Canyon Middle School, Agoura Hills, California, United States Los Cerritos Middle School, Thousand Oaks, California, United States Lutheran Church in Malaysia and Singapore