The comic book character Spider-Man has had much media attention due to his popularity as a superhero, as have his villains. Here is a list of his primary villains that have undergone media attention, such as in films, television, and video games, as well as some villains who debuted in the TV series.
Film
This is a list of Spider-Man enemies that have been in Sam Raimi's Spider-Man film trilogy, Marc Webb's The Amazing Spider-Man films, the Marvel Cinematic Universe (MCU), and Sony's Spider-Man Universe.
The movies in the original trilogy also introduce Dylan Baker as Dr. Curt Connors, the man who in the comics becomes the Lizard. Still, this transformation never took place during Raimi's tenure as director. Mendel Stromm was portrayed by actor Ron Perkins in Spider-Man. However, he did not become a villain while Spider-Man 2 features Daniel Gillies as John Jameson, whose transformation into the Man-Wolf is not depicted in the film. Additionally, the Kingpin was featured prominently in the Mark Steven Johnson film Daredevil, where he was portrayed by Michael Clarke Duncan.
In The Amazing Spider-Man, the Lizard is the villain. Irrfan Khan also portrays the antagonistic Dr. Ratha in that film. In The Amazing Spider-Man 2, Felicity Jones plays Felicia Hardy, the alter ego of Black Cat, but her version of Black Cat was never shown.
In Spider-Man: Homecoming, Michael Mando appears as Mac Gargan, but did not become Scorpion, eventually donning the mantle in Spider-Man: Brand New Day. In Spider-Man: Far From Home, Jake Gyllenhaal portrays Mysterio, who was originally to be played by Bruce Campbell in Raimi's canceled fourth film.
Live-action VillainFilmActorJanice LincolnSpider-Man: Far From HomeClaire RushbrookFelicia HardyThe Amazing Spider-Man 2Felicity JonesDennis CarradineSpider-Man (2002)Spider-Man 3The Amazing Spider-Man (2012)Michael PapajohnLeif GantvoortCalypso EziliKraven the Hunter (2024)Ariana DeBoseCletus KasadyVenom (2018)Venom: Let There Be CarnageWoody HarrelsonDmitri SmerdyakovSpider-Man: Far From HomeKraven the Hunter (2024)Numan AcarFred HechingerRandy ValeSpider-Man: HomecomingChristopher BerryDr. Otto OctaviusSpider-Man 2Spider-Man: No Way HomeAlfred MolinaDonald MenkenThe Amazing Spider-Man 2Colm FeoreMax DillonThe Amazing Spider-Man 2Spider-Man: No Way HomeJamie FoxxKarl FiersThe Amazing Spider-Man 2Bill HeckKris KeatingKraven the Hunter (2024)Christopher AbbottGustav FiersThe Amazing Spider-Man (2012)The Amazing Spider-Man 2Michael MasseeHarry OsbornSpider-Man (2002)Spider-Man 2Spider-Man 3The Amazing Spider-Man 2James FrancoDane DeHaanNorman OsbornSpider-Man (2002)Spider-Man 2Spider-Man 3Spider-Man: No Way HomeThe Amazing Spider-Man 2Willem DafoeChris CooperNed LeedsSpider-Man: HomecomingAvengers: Infinity WarAvengers: EndgameSpider-Man: Far From HomeSpider-Man: No Way HomeSpider-Man: Brand New DayJacob BatalonWilson FiskThe Trial of the Incredible HulkDaredevil (film)John Rhys-DaviesMichael Clarke DuncanKnullVenom: The Last DanceAndy SerkisSergei KravinoffKraven the Hunter (2024)Aaron Taylor-JohnsonDr. Curt ConnorsSpider-Man 2Spider-Man 3The Amazing Spider-Man (2012)Spider-Man: No Way HomeDylan BakerRhys IfansJohn JamesonSpider-Man 2Venom (2018)Daniel GilliesChris O'HaraDr. Michael MorbiusBlade (1998)Morbius (2022)Stephen NorringtonJared LetoQuentin BeckSpider-Man: Far From HomeSpider-Man: No Way HomeJake GyllenhaalAaron DavisSpider-Man: HomecomingSpider-Man: Across the Spider-VerseDonald GloverFrank CastleThe Punisher (1989)The Punisher (2004)Punisher: War ZoneThe Punisher: One Last KillSpider-Man: Brand New DayDolph LundgrenThomas JaneRay StevensonJon BernthalDr. Ashley KafkaThe Amazing Spider-Man 2Marton CsokasAleksei SytsevichThe Amazing Spider-Man 2Kraven the Hunter (2024)Paul GiamattiAlessandro NivolaCarlton DrakeVenom (2018)Riz AhmedProfessor Mendel StrommSpider-Man (2002)Superhero Movie (2008)Ron PerkinsBrent SpinerFlint MarkoSpider-Man 3Spider-Man: No Way HomeThomas Haden ChurchMac GarganSpider-Man: HomecomingSpider-Man: Brand New DayMichael MandoLiz AllanSpider-Man (2002)Spider-Man: HomecomingSally LivingstoneLaura HarrierAnne WeyingVenom (2018)Venom: Let There Be CarnageMichelle WilliamsHerman SchultzSpider-Man: HomecomingBokeem WoodbineJackson BriceSpider-Man: HomecomingLogan Marshall GreenFrances BarrisonVenom: Let There Be CarnageNaomie HarrisAntonia DreykovBlack WidowThunderbolts*Olga KurylenkoPhineas MasonSpider-Man: HomecomingMichael ChernusLonnie LincolnSpider-Man: Brand New DayMarvin "Krondon" Jones IIIPatrick MulliganVenom: Let There Be CarnageVenom: The Last DanceSean DelaneyStephen GrahamAlistair SmytheThe Amazing Spider-Man 2B. J. NovakEddie BrockSpider-Man 3Venom (2018)Venom: Let There Be CarnageSpider-Man: No Way HomeVenom: The Last DanceTopher GraceTom HardyAdrian ToomesSpider-Man: HomecomingMorbius (2022)Michael Keaton
Animation VillainFilmActorRichard FiskSpider-Man: Into the Spider-VerseBasement photo cameoOlivia OctaviusKathryn HahnOtto OctaviusSpider-Man: Into the Spider-VerseSpider-Man: Across the Spider-Versenon-speaking cameoOtto OctaviusSpider-Man: Across the Spider-Versenon-speaking cameoNorman OsbornSpider-Man: Into the Spider-Verse Spider-Man: Across the Spider-VerseJorma Tacconenon-speaking cameoDmitri Smerdyakovnon-speaking cameoDaniel Britonon-speaking cameosJoseph Martellonon-speaking cameosWilson FiskLiev SchreiberPeter Parkernon-speaking cameoJack QuaidJackson Bricenon-speaking cameoRaymond BlochBasement photo cameoAaron DavisMahershala AliFrank CastleIron Man: Rise of TechnovoreAvengers Confidential: Black Widow & PunisherNorman ReedusBrian BloomMaximus GarganSpider-Man: Into the Spider-VerseJoaquín CosíoHerman SchultzSpider-Man: Into the Spider-VerseSpider-Man: Across the Spider-VerseEarth-1610B, Captured by Spider-Society and Earth-42Jonathan Ohnnnon-speaking cameoJason SchwartzmanLonnie LincolnSpider-Man: Into the Spider-VerseSpider-Man: Beyond the Spider-VerseMarvin "Krondon" Jones IIIAdrian ToomesSpider-Man: Across the Spider-VerseJorma Taccone
Television Several Spider-Man villains have made appearances in Spider-Man animated television series, other Marvel Comics related shows, the Marvel Cinematic Universe (MCU), and Sony's Spider-Man Universe. Vincent D'Onofrio portrays the Kingpin in Marvel Television's Netflix series Daredevil and the Disney+ series Hawkeye, Echo, and Daredevil: Born Again. Jon Bernthal portrays the Punisher in Marvel Television's Netflix series Daredevil and The Punisher as well as the Disney+ series Daredevil: Born Again. Also, in Wolverine and the X-Men, there was a character that closely resembles Shadrac. Here is a listing in alphabetical order.
Live-action VillainTelevisionActorBlack CatSpider-NoirLi Jun Li (alter ego only)(Marvel Noir version)KingpinDaredevil (TV series)Hawkeye (TV series)Echo (TV series)Daredevil: Born AgainVincent D'OnofrioMegawattSpider-NoirAndrew Lewis Caldwell (Marvel Noir version)OwlDaredevil (TV series)Bob GuntonPunisherDaredevil (TV series)The Punisher (TV series)Daredevil: Born AgainJon BernthalSandmanSpider-NoirJack Huston (Marvel Noir version)SilvermaneBrendan Gleeson (Marvel Noir version)TombstoneAbraham Popoola (Marvel Noir version)
Animation