CPE may refer to:

Biochemistry Carbapenemase-producing enterobacteriaceae, a "superbug" resistant to antibiotics Carboxypeptidase E, an enzyme involved in the biosynthesis of neuropeptides and peptide hormones Clostridium perfringens enterotoxin, a contributor to food poisoning Cytopathic effect, changes in cells caused by viruses Cytoplasmic polyadenylation element, an RNA sequence Chlorinated polyethylene, a thermoplastic polymer Core promoter element, in DNA, initiating gene transcription

Telecommunications Customer-premises equipment, any equipment which is the property of the network operator and located on the customer premises

Science Carnian pluvial episode/event, a climatic episode and minor extinction-radiation event in the Triassic Carbon paste electrode, a special type of electrodes used in electrochemistry Charged-particle equilibrium Computer engineering Constant phase element of an equivalent electrical circuit

Education Certificate of Primary Education, an academic qualification in Mauritius awarded upon the completion of primary school Certificate of Proficiency in English, a general English exam provided by the University of Cambridge Certified Professional Electrologist, board certification credential for permanent hair removal specialists Clinical pastoral education, training in pastoral care for religious workers Coalition on Psychiatric Emergencies, a coalition of organizations dedicated to improving care for mental health emergencies Common Professional Examination, a course which allows non-law graduates in England and Wales to convert to law after university Continuing professional education, or continuing professional development, is the means by which professionals maintain and develop the qualities required in their working lives École supérieure de chimie physique électronique de Lyon (CPE Lyon), a French engineering school Kentucky Council on Postsecondary Education Committee for Private Education, an accreditation body for private schools and tertiary education providers in Singapore

Business Centrally planned economy First Employment Contract (contrat première embauche), a French form of work contract, retracted by the government in Spring 2006 Cost Per Enplanement, a term used in commercial aviation regarding airport costs Cost per engagement, an online advertising selling model in which the vendor defines the "engagement" as form of currency or metric

Organisations Centristi per l'Europa (Centrists for Europe), an Italian political party Communist Party of England (Marxist-Leninist), former name of Revolutionary Communist Party of Britain (Marxist–Leninist) CPE (investment firm), Chinese company Creative Power Entertaining, Chinese animation company

Other uses Chinese Pidgin English, a pidgin language spoken in parts of China in the 17th to 19th centuries. Common Platform Enumeration, a component of the Security Content Automation Protocol (SCAP) CPE, IATA airport code for Ing. Alberto Acuña Ongay International Airport in Campeche, Mexico Carl Philipp Emanuel Bach (1714–1788), German Classical period musician and composer Communist Party of Estonia