Nwosu is a common Nigerian surname of Igbo origin, which means "child dedicated to the gods".

Notable people Alice Nwosu (born 1984), Nigerian runner Henry Nwosu (1963–2026), Nigerian football manager Julius Nwosu (born 1971), Nigerian basketball player Ken Nwosu, British actor Nwankwo Christian Nwosu Kanu (born 1976), Nigerian footballer Uchenna Nwosu (born 1996), American football player