Pocomoke may refer to:
The Pocomoke people, a historic Native American tribe Pocomoke City, Maryland, a town Pocomoke Indian Nation, a cultural heritage group and nonprofit based in Maryland Pocomoke River, a tributary of the Chesapeake Bay on the Eastern Shore of Maryland Pocomoke Sound, a bay of the Chesapeake Bay Pocomoke State Forest, Maryland USS Pocomoke, the name of three United States Navy ships