DPB may stand for: Government Domestic Purposes Benefit, in the New Zealand social security system Defense Policy Board, of the US Department of Defense

Science and technology Decoded Picture Buffer, used by video decoders Diffuse panbronchiolitis, a lung disease Disinfection by-product, in water treatment

Transport Deer Park Bypass, Melbourne, Australia Depok Baru railway station, Depok, Indonesia USCG deployable pursuit boat Dopravný podnik Bratislava, a Slovakian public transport operator

Other uses Deutscher Pfadfinderbund (1945) Discounted Payback, an engineering economics measure