Sakellarios (), genitive and feminine form Sakellariou (), is a Greek surname deriving from the Byzantine office of sakellarios. Notable people with the surname include:
Aggeliki Sakellariou Greek linguist and philologist Alekos Sakellarios (1913–1991), Greek film director Alexandros Sakellariou (1887–1982), Greek admiral and defence minister Georgios Sakellarios (1765–1838), Greek physician of Ali Pasha Pericles A. Sakellarios (1905–1985), Greek architect Rita Sakellariou (1934–1999), Greek singer
See also Sakellaridis Sakellaropoulos