Samuel Johnston or Sam Johnston may refer to: Sam Johnston (Yukon politician) (born 1935), politician in the Yukon, Canada Sam Johnston (New Brunswick politician), politician in the New Brunswick, Canada Sam Johnston (wrestler) (born 1987), American professional wrestler better known as Sami Callihan Sammy Johnston (1967–2025), Scottish footballer Samuel Johnston (1733–1816), American lawyer and statesman SS Samuel Johnston, a Liberty ship Samuel Johnston (footballer) (1866–1910), Irish footballer Samuel Johnston (Waterview) (1840–1924), Australian pioneer

See also Samuel Johnson (disambiguation)