Kisugi is a Japanese surname. Notable people with the surname include:
Takao Kisugi, singer/composer Etsuko Kisugi, Takao's sister and a lyricist
Fictional characters Ai, Hitomi, and Rui Kisugi, the protagonists of Cat's Eye Hiroto Kisugi of Otogi-Jūshi Akazukin Makiko Kisugi (also known as Fear Ghoul) a doctor in Boogiepop at Dawn Teppei Kisugi of Captain Tsubasa