GS5 or GS-5 may refer to:
Series 3 of Ghost Squad (TV series) Samsung Galaxy S5, a 2014 smart phone Gyakuten Saiban 5, a 2013 video game GS-5, a pay grade in the General Schedule (US civil service pay scale) Southern Pacific class GS-5, a steam locomotive Gaisrinė sauga, 5 grupė (VGTU) A PlayStation 5-themed Famiclone