MTX, mtx, or MtX may refer to:
Automobiles MTX (automobile), an automobile company in the Czech Republic Ford MTX transmission, a 4 or 5-speed manual transaxle Ford MTX-75 transmission, a 5-speed transmission
Science and technology Memotech MTX, a series of computers Maitotoxin, a biotoxin produced by the dinoflagellate Gambierdiscus toxicus Methotrexate, a drug used to treat cancer and autoimmune diseases
Other uses MtX (gender) Microtransaction, purchasing goods with micropayments within a game MTX Audio, a manufacturer of audio electronics The Mr. T Experience, a punk rock band