Wetherill is an English language surname, and may refer to:
Anna Wetherill Olmsted (1888–1961), American curator and museum director Charles M. Wetherill, American chemist Christine Wetherill (1878–1922), heiress to the Pittsburgh Paint Company, dramatist and arts patron David Wetherill, British table tennis player George Wetherill, American physicist Louisa Wade Wetherill (1877–1945), American explorer and trader
Richard Wetherill, American archaeologist Roderick Wetherill, American Army general
See also 2128 Wetherill Fort Wetherill Wetherill Park, New South Wales Wetherell Weatherall Wetherall