Harpagophagus is an extinct genus of large, mostly carnivorous bone-crushing mammals of the family Amphicyonidae endemic to Europe during the Oligocene living from 33.9 to 23.03 Ma and existed for approximately . Paleobiology Database: Drassonax Basic info.

Taxonomy Harpagophagus was named by De Bonis (1971). It is not extant. Its type is Harpagophagus sanguinensis. It was assigned to Amphicyonidae by De Bonis (1971) and Carroll (1988).L. De Bonis. 1971. Deux nouveaux carnassiers de Phosphorites du Quercy. Annales de Paléontologie 57:117-127R. L. Carroll. 1988. Vertebrate Paleontology and Evolution. W. H. Freeman and Company, New York 1-698

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