Hopley is an English surname. Notable people with the surname include:
Arthur Hopley (1906–1981), British Anglican priest Catherine Cooper Hopley (1817–1911), English author and naturalist Damian Hopley (born 1970), English rugby player Edward Hopley (1816–1869), English painter Geoffrey Hopley (1891–1915), English cricketer Georgia Hopley (1858–1944), American journalist, political figure, and prohibition agent John Hopley (athlete), (1883–1951), South African sportsman John Hopley (editor) (1821–1904), British-American newspaperman from Ohio Hannes Hopley (born 1981), South African discus thrower Lizzie Hopley, British actress and writer Mark Hopley (born 1984), English rugby player
See also Hopley Yeaton (1739–1812), the first officer commissioned into the U.S. Revenue Cutter Service Cornell George Hopley-Woolrich, (1903–1968), American novelist and shortstory writer