Samudrala is a Telugu surname and may refer to:
Samudrala Sr. (1902–1968), writer, producer, and director Samudrala Jr. (1923–1985), film writer and son of Samudrala Sr. Samudrala Venugopal Chary (fl. 1985–2009), Indian politician Ram Samudrala (born 1972), Indian-American professor of bioinformatics
See also Samandar (disambiguation) Samudra, Sanskrit word for the ocean