Mizushima (written: lit. "water island") is a Japanese surname. Notable people with the surname include:
Hiro Mizushima (born 1984), Japanese actor, producer, writer, and creative director Koichi Mizushima (born 1965), Japanese former gymnast Koichi Mizushima (scientist) (born 1941), Japanese researcher Musashi Mizushima (born 1964), Japanese former professional footballer Natsumi Mizushima (born 1984), Japanese retired professional wrestler , Japanese women's basketball player Takahiro Mizushima (born 1976), Japanese voice actor Teruko Mizushima (1920–1996), Japanese inventor of timebanks Tsutomu Mizushima (born 1965), Japanese anime director Satoru Mizushima (born 1949), Japanese film maker Seiji Mizushima (born 1966), Japanese anime director Shinji Mizushima (born 1939), Japanese manga artist Yū Mizushima (born 1956), Japanese voice actor