A Twinkie is a snack cake with a cream filling.

Twinkie(s) may also refer to:

Twinkie (slur), a pejorative term Twinkie Clark (b. 1954), a musician Twinkies, a nickname for the Minnesota Twins Twinkie, a character from the Fast & Furious franchise most notably from The Fast and the Furious: Tokyo Drift

See also Twinkie defense, a legal strategy Twinky, the original British title of Lola (1969 film) Twink (disambiguation)