Woodruff House may refer to:
United States Connecticut Capt. Samuel Woodruff House, Southington Charles Woodruff House, Southington, NRHP-listed Ezekiel Woodruff House, Southington Jotham Woodruff House, Southington Urbana Woodruff House, Southington Woodruff House, Southington Stanley-Woodruff-Allen House, West Hartford
Georgia Ernest Woodruff House, Columbus, NRHP-listed Henry Lindsay Woodruff House, Columbus, NRHP-listed Henry Lindsay Woodruff Second House, Columbus, NRHP-listed Cowles–Woodruff House, Macon
Utah Asahel Hart Woodruff House, Salt Lake City, NRHP-listed Wilford Woodruff Farm House, Salt Lake City, NRHP-listed Woodruff Villa, Salt Lake City, NRHP-listed Woodruff-Riter House, Salt Lake City, NRHP-listed Woodruff Stake House, Woodruff
Other William Woodruff House, Little Rock, Arkansas S. H. Woodruff Residence, Los Angeles, California, LAHCM No. 681 Woodruff House (Hillside, New Jersey) Woodruff House (Cornwall, New York) William H. Woodruff House, Green Township, Ohio, NRHP-listed Charles Woodruff House (Wyoming, Ohio), NRHP-listed Jacob Woodruff House, Ripon, Wisconsin