OWB may refer to:

Oracle Warehouse Builder Origyn Web Browser aka Odyssey Web Browser The IATA airport code for Owensboro-Daviess County Regional Airport in Owensboro, Kentucky, United States A handgun holster worn outside the waistband Old World Blues, a DLC in Fallout: New Vegas

Old World Blues, a mod for the computer wargame Hearts of Iron IV

ÖWB may refer to:

Österreichisches Wörterbuch (Austrian dictionary)