Sesto may refer to:
People
Surname Camilo Sesto (1946–2019), Spanish singer Cesare da Sesto, (1477–1523) Italian painter Count Sesto, an Italian noble title
Given name Sesto Bruscantini (1919–2003), Italian opera singer Sesto Pals (–2008), Romanian writer Sesto Prete (1919–1991), Italian-American philologist Sesto Rocchi (1909–1991), Italian luthier
Places Sesto al Reghena, Pordenone, Italy Sesto Calende, Varese, Italy Sesto Campano, Isernia, Italy Sesto ed Uniti, Cremona, Italy Sesto Fiorentino, Florence, Italy Sesto San Giovanni, Milano, Italy Sexten (Italian: Sesto), Bolzano, Italy
See also Sestos, an ancient city in Turkey Sestu, an Italian municipality in the Province of Cagliari