The Emanuel Building, also known as the Bank of Mobile and Staples-Pake Building, is a historic commercial building in Mobile, Alabama, United States. The three-story masonry structure was built in 1850 and then remodeled several times over the next century. See also: It was placed on the National Register of Historic Places on March 21, 1978.

The significance of the Staples-Pake Building is both architectural and commercial. Initially constructed in the 1850's as office space by a Mobile cotton broker, Jonathan Emanuel, the structure was remodeled in 1903 by George Bigelow Rogers.

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