Powder River may refer to:
Places Powder River (Wyoming and Montana), a tributary to the Yellowstone River in Wyoming and Montana, United States Powder River Country, the area around the river Powder River Basin, a coal-rich geologic basin Powder River Pass, a mountain pass in the Big Horn Mountains of Wyoming Powder River County, Montana, a county in southeastern Montana Powder River, Wyoming, a populated place in Natrona County Powder River station, a former train station in Natrona County Powder River Station-Powder River Crossing, an abandoned settlement in Wyoming Powder River (Oregon), a tributary to the Snake River in Oregon, United States
Military events
Powder River Expedition (1865), a military expedition through the Powder River Country Powder River Battles (1865) Powder River Massacre Powder River War, or Red Cloud's War, an 1866 to 1868 armed conflict Battle of Powder River, an 1876 battle fought during the Black Hills War War on Powder River, or the Johnson County War, an 1889 to 1893 range war in Wyoming
Sports
Powder River pass, a football play in 1954 giving Arkansas a 6-0 win over Ole Miss
Transportation
USS LSM(R)-519, renamed Powder River in 1955
Media
Powder River (film), a 1953 American Western directed by Louis King Powder River (radio), an American radio drama series Powder River, a 1989 album by Chris LeDoux