William F. Smith may refer to:
William F. Smith (American football) (1888–?), American college football player and coach William F. Smith (New York politician) (1901–1950), American lawyer and politician William Farrar Smith (1824–1903), Union Army general William Francis Smith (1904–1968), U.S. District Court judge William French Smith (1917–1990), U.S. Attorney General William Forgan Smith (1887–1952), Premier of the Australian state of Queensland William F. Smith, Jr. (died 1945), lieutenant colonel in the U.S. Army Air Forces who died in the 1945 Empire State Building B-25 crash
See also William Smith (disambiguation)