SBU may refer to:
Military and defense
Security Service of Ukraine or Sluzhba Bezpeky Ukrayiny (SBU) Sensitive but unclassified, a U.S. designation of information Vought SBU Corsair, an aircraft Special Boarding Unit, Japanese special forces unit
Universities San Beda University, Manila, Philippines Sarala Birla University, Jharkhand, India Shahid Beheshti University, Tehran, Iran Southwest Baptist University, Missouri, US Stony Brook University, New York, US University of Health Sciences (Turkey) ()
Business Siberian Business Union, a Russian holding company Stanbic Bank Uganda Limited Strategic business unit
Technologies Standard Build Unit in Linux From Scratch Sense and Braking Unit, an end-of-train device
Other uses SBU, the National Rail station code for Southbury railway station, London, England Songbei District, a district of Harbin, China Swedish Agency for Health Technology Assessment and Assessment of Social Services