Lesh () is both a surname and a given name. Notable people with the name include:
As a surname Fyodor Lesh (1840–1903), Russian physician Leonid Lesh (1862–1934), Russian general Phil Lesh (1940–2024), American musician Richard Lesh, American professor Ulysses Samuel Lesh (1868–1965), American politician
As a given name Lesh Shkreli (born 1957), Yugoslav footballer
See also Lesch, a surname Loesch Losch LESH Phil Lesh and Friends Lezhë